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Circulating LOXL2 Levels Reflect Severity of Intestinal Fibrosis and GALT CD4(+) T Lymphocyte Depletion in Treated HIV Infection
BACKGROUND: Incomplete immune reconstitution may occur despite successful antiretroviral therapy (ART). Gut-associated lymphoid tissue (GALT) fibrosis may contribute via local CD4(+) T lymphocyte depletion, intestinal barrier disruption, microbial translocation, and immune activation. METHODS: In a...
Autores principales: | Seang, Sophie, Somasunderam, Anoma, Nigalye, Maitreyee, Somsouk, Ma, Schacker, Timoty W., Sanchez, Joyce L., Hunt, Peter W., Utay, Netanya S., Lake, Jordan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pathogens and Immunity
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542020/ https://www.ncbi.nlm.nih.gov/pubmed/28782046 http://dx.doi.org/10.20411/pai.v2i2.180 |
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