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Triptolide mitigates radiation-induced pneumonitis via inhibition of alveolar macrophages and related inflammatory molecules
Ionizing radiation-induced pulmonary injury is a major limitation of radiotherapy for thoracic tumors. We have demonstrated that triptolide (TPL) could alleviate IR-induced pneumonia and pulmonary fibrosis. In this study, we explored the underlying mechanism by which TPL mitigates the effects of rad...
Autores principales: | Chen, Chun, Yang, Shanmin, Zhang, Mei, Zhang, Zhenhuan, Zhang, Steven B., Wu, Bing, Hong, Jinsheng, Zhang, Weijian, Lin, Jianhua, Okunieff, Paul, Zhang, Lurong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542172/ https://www.ncbi.nlm.nih.gov/pubmed/28415830 http://dx.doi.org/10.18632/oncotarget.16456 |
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