Clinically significant sub-clonality for common drivers can be detected in 26% of KRAS/EGFR mutated lung adenocarcinomas

Genetic sub-clonality has been described in multiple malignancies, however the presence of sub-clonality for major drivers in lung adenocarcinoma and its clinical significance is a subject under debate. Using molecular and morphometric approach, 347 lung adenocarcinoma samples were analyzed for KRAS...

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Detalles Bibliográficos
Autores principales: Simon, Einav, Bick, Tova, Sarji, Shada, Shentzer, Talia, Prinz, Elad, Yehiam, Liza, Sabo, Edmond, Ben-Izhak, Ofer, Hershkovitz, Dov
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542222/
https://www.ncbi.nlm.nih.gov/pubmed/28501852
http://dx.doi.org/10.18632/oncotarget.17399

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542222/
https://www.ncbi.nlm.nih.gov/pubmed/28501852
http://dx.doi.org/10.18632/oncotarget.17399

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