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Dual-negative expression of Nrf2 and NQO1 predicts superior outcomes in patients with non-small cell lung cancer

Functional studies in non-small cell lung cancer (NSCLC) patients revealed that hyperactivation of the NF-E2-related factor 2 (Nrf2) pathway facilitates tumor growth. We examined the usefulness of Nrf2 and NQO1 as indicators of prognosis in NSCLC. Tumor and adjacent non-tumor tissue samples were col...

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Detalles Bibliográficos
Autores principales: Tong, Ying-Hui, Zhang, Bo, Yan, You-You, Fan, Yun, Yu, Jia-Wen, Kong, Si-Si, Zhang, Dan, Fang, Luo, Su, Dan, Lin, Neng-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542223/
https://www.ncbi.nlm.nih.gov/pubmed/28501854
http://dx.doi.org/10.18632/oncotarget.17403