Oncogenic MNK signalling regulates the metastasis suppressor NDRG1

The protein N-myc down-regulated gene 1 (NDRG1) represses tumour metastasis. It is phosphorylated at several sites by serum and glucocorticoid-regulated kinase 1 (SGK1). Here we show that NDRG1 is also regulated by the oncogenic MAP kinase-interacting kinase (MNK) pathway, a target for cancer therap...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Shuye, Wang, Xuemin, Proud, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542254/
https://www.ncbi.nlm.nih.gov/pubmed/28545025
http://dx.doi.org/10.18632/oncotarget.17555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542254/
https://www.ncbi.nlm.nih.gov/pubmed/28545025
http://dx.doi.org/10.18632/oncotarget.17555

Ejemplares similares