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Hypermethylation of NDN promotes cell proliferation by activating the Wnt signaling pathway in colorectal cancer

The progression of CRC is a multistep process involving several genetic changes or epigenetic modifications. NDN is a member of the MAGE family, encoding a protein that generally suppresses cell proliferation and acting as a transcriptional repressor. Immunohistochemical staining revealed that the e...

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Detalles Bibliográficos
Autores principales: Hu, Yu-Han, Chen, Qing, Lu, Yan-Xia, Zhang, Jian-Ming, Lin, Chun, Zhang, Fan, Zhang, Wen-Juan, Li, Xiao-Min, Zhang, Wei, Li, Xue-Nong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542259/
https://www.ncbi.nlm.nih.gov/pubmed/28521288
http://dx.doi.org/10.18632/oncotarget.17580