Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism

5-Fluorouracil (5-FU) is a widely used chemotherapeutic drug in colorectal cancer. Previous studies showed that 5-FU modulates RNA metabolism and mRNA expression. In addition, it has been reported that 5-FU incorporates into the RNAs constituting the translational machinery and that 5-FU affects the...

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Detalles Bibliográficos
Autores principales: Bash-Imam, Zeina, Thérizols, Gabriel, Vincent, Anne, Lafôrets, Florian, Espinoza, Micaela Polay, Pion, Nathalie, Macari, Françoise, Pannequin, Julie, David, Alexandre, Saurin, Jean-Christophe, Mertani, Hichem C., Textoris, Julien, Auboeuf, Didier, Catez, Frédéric, Dalla Venezia, Nicole, Dutertre, Martin, Marcel, Virginie, Diaz, Jean-Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542262/
https://www.ncbi.nlm.nih.gov/pubmed/28515355
http://dx.doi.org/10.18632/oncotarget.17597

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