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Autophagy and mitophagy in the context of doxorubicin-induced cardiotoxicity
Doxorubicin (Dox) is a cytotoxic drug widely incorporated in various chemotherapy protocols. Severe side effects such as cardiotoxicity, however, limit Dox application. Mechanisms by which Dox promotes cardiac damage and cardiomyocyte cell death have been investigated extensively, but a definitive p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals LLC
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542301/ https://www.ncbi.nlm.nih.gov/pubmed/28445146 http://dx.doi.org/10.18632/oncotarget.16944 |