Hemoglobin Stimulates the Expression of Adamts-5 and -9 by Synovial Cells; A Possible Cause of Cartilage Damage after Intra-articular Bleeding

OBJECTIVES: A disintegrin and metalloprotease with thrombospondin motifs (ADAMTS)-5 and -9 play an important pathologic role in matrix degeneration. Aggrecanase-mediated aggrecan degradation is a significant and critical event in early-stage osteoarthritis. To determine the effect of hemoglobin (Hb)...

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Detalles Bibliográficos
Autores principales: Tajima, Takuya, Chosa, Etsuo, Taniguchi, Noboru, YAMAGUCHI, Nami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542312/
http://dx.doi.org/10.1177/2325967117S00327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542312/
http://dx.doi.org/10.1177/2325967117S00327

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