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Quantitative and qualitative estimation of atherosclerotic plaque burden in vivo at 7T MRI using Gadospin F in comparison to en face preparation evaluated in ApoE KO mice

BACKGROUND: The aim of the study was to quantify atherosclerotic plaque burden by volumetric assessment and T1 relaxivity measurement at 7T MRI using Gadospin F (GDF) in comparison to en face based measurements. METHODS AND RESULTS: 9-weeks old ApoE(-/-) (n = 5 for each group) and wildtype mice (n =...

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Detalles Bibliográficos
Autores principales: Jung, Caroline, Christiansen, Sabine, Kaul, Michael Gerhard, Koziolek, Eva, Reimer, Rudolph, Heeren, Jörg, Adam, Gerhard, Heine, Markus, Ittrich, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542445/
https://www.ncbi.nlm.nih.gov/pubmed/28771481
http://dx.doi.org/10.1371/journal.pone.0180407