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Eicosapentaenoic acid prevents arterial calcification in klotho mutant mice
BACKGROUND: The klotho gene was identified as an “aging-suppressor” gene that accelerates arterial calcification when disrupted. Serum and vascular klotho levels are reduced in patients with chronic kidney disease, and the reduced levels are associated with arterial calcification. Intake of eicosape...
Autores principales: | Nakamura, Kazufumi, Miura, Daiji, Saito, Yukihiro, Yunoki, Kei, Koyama, Yasushi, Satoh, Minoru, Kondo, Megumi, Osawa, Kazuhiro, Hatipoglu, Omer F., Miyoshi, Toru, Yoshida, Masashi, Morita, Hiroshi, Ito, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542469/ https://www.ncbi.nlm.nih.gov/pubmed/28771600 http://dx.doi.org/10.1371/journal.pone.0181009 |
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