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Novel application of the published kinase inhibitor set to identify therapeutic targets and pathways in triple negative breast cancer subtypes
Triple negative breast cancers (TNBCs) have high recurrence and metastasis rates. Acquisition of a mesenchymal morphology and phenotype in addition to driving migration is a consequential process that promotes metastasis. Although some kinases are known to regulate a mesenchymal phenotype, the role...
Autores principales: | Matossian, Margarite D., Elliott, Steven, Hoang, Van T., Burks, Hope E., Phamduy, Theresa B., Chrisey, Douglas B., Zuercher, William J., Drewry, David H., Wells, Carrow, Collins-Burow, Bridgette, Burow, Matthew E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542472/ https://www.ncbi.nlm.nih.gov/pubmed/28771473 http://dx.doi.org/10.1371/journal.pone.0177802 |
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