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An evolutionarily conserved glycine-tyrosine motif forms a folding core in outer membrane proteins

An intimate interaction between a pair of amino acids, a tyrosine and glycine on neighboring β-strands, has been previously reported to be important for the structural stability of autotransporters. Here, we show that the conservation of this interacting pair extends to nearly all major families of...

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Detalles Bibliográficos
Autores principales: Michalik, Marcin, Orwick-Rydmark, Marcella, Habeck, Michael, Alva, Vikram, Arnold, Thomas, Linke, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542473/
https://www.ncbi.nlm.nih.gov/pubmed/28771529
http://dx.doi.org/10.1371/journal.pone.0182016

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