Cargando…

Increased serum thrombomodulin level is associated with disease severity and mortality in pediatric sepsis

BACKGROUND: Endothelial dysfunction plays an important role in the pathophysiology of sepsis. As previously reported, the serum thrombomodulin is elevated in diseases associated with endothelial injury. OBJECTIVE: The aim of this study was to investigate the association of serum thrombomodulin level...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Jainn-Jim, Hsiao, Hsiang-Ju, Chan, Oi-Wa, Wang, Yu, Hsia, Shao-Hsuan, Chiu, Cheng-Hsun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542536/ https://www.ncbi.nlm.nih.gov/pubmed/28771554 http://dx.doi.org/10.1371/journal.pone.0182324

Ejemplares similares

Decreased ADAMTS 13 Activity is Associated With Disease Severity and Outcome in Pediatric Severe Sepsis
por: Lin, Jainn-Jim, et al.
Publicado: (2016)

Clinical features and outcomes of invasive pneumococcal disease in a pediatric intensive care unit
por: Hsiao, Hsiang-Ju, et al.
Publicado: (2015)

Hemodynamic monitoring and management of pediatric septic shock
por: Lee, En-Pei, et al.
Publicado: (2022)

Risk Factors and Neurologic Outcomes Associated With Resuscitation in the Pediatric Intensive Care Unit
por: Lee, En-Pei, et al.
Publicado: (2022)

Predictors of neurologic outcomes and mortality in physically abused and unintentionally injured children: a retrospective observation study
por: Lee, En-Pei, et al.
Publicado: (2023)

Cardiopulmonary failure in children infected with Enterovirus A71
por: Hsia, Shao-Hsuan, et al.
Publicado: (2020)

Cutoff Values of Hemodynamic Parameters in Pediatric Refractory Septic Shock
por: Lee, En-Pei, et al.
Publicado: (2022)

Hemodynamic Analysis of Pediatric Septic Shock and Cardiogenic Shock Using Transpulmonary Thermodilution
por: Lee, En-Pei, et al.
Publicado: (2017)

Early High-Dose Methylprednisolone Therapy Is Associated with Better Outcomes in Children with Acute Necrotizing Encephalopathy
por: Chang, Han-Pi, et al.
Publicado: (2022)

Occult child abuse presenting as pneumatosis intestinalis and portomesenteric venous gas - a case report
por: Lee, En-Pei, et al.
Publicado: (2019)

Comparison of Predictive Powers for Mortality between Systemic Vascular Resistance Index and Serum Lactate in Children with Persistent Catecholamine-Resistant Shock
por: Lee, En-Pei, et al.
Publicado: (2020)

High-Flow Nasal Cannula Therapy in Children With Acute Respiratory Distress With Hypoxia in A Pediatric Intensive Care UnitA Single Center Experience
por: Chang, Chih-Ching, et al.
Publicado: (2021)

Effect of Audiovisual Cardiopulmonary Resuscitation Feedback Device on Improving Chest Compression Quality
por: Lin, Chia-Ying, et al.
Publicado: (2020)

Clinical role of low hemoglobin ratio in poor neurologic outcomes in infants with traumatic intracranial hemorrhage
por: Lee, En-Pei, et al.
Publicado: (2020)

The Utility of a Point-of-Care Transcranial Doppler Ultrasound Management Algorithm on Outcomes in Pediatric Asphyxial Out-of-Hospital Cardiac Arrest – An Exploratory Investigation
por: Lin, Jainn-Jim, et al.
Publicado: (2022)

Risk Factors for Tracheobronchomalacia in Preterm Infants With Bronchopulmonary Dysplasia
por: Su, Ya-Ting, et al.
Publicado: (2021)

Analysis of clinical parameters and echocardiography as predictors of fatal pediatric myocarditis
por: Chang, Yi-Jung, et al.
Publicado: (2019)

Factors Associated With In-hospital Mortality of Children With Acute Fulminant Myocarditis on Extracorporeal Membrane Oxygenation
por: Lee, En-Pei, et al.
Publicado: (2020)

Evaluation of diaphragmatic function in mechanically ventilated children: An ultrasound study
por: Lee, En-Pei, et al.
Publicado: (2017)

Clinical Significance of Nadir Hemoglobin in Predicting Neurologic Outcome in Infants With Abused Head Trauma
por: Lee, En-Pei, et al.
Publicado: (2020)

Epileptiform Discharge and Electrographic Seizures during the Hypothermia Phase as Predictors of Rewarming Seizures in Children after Resuscitation
por: Lin, Jainn-Jim, et al.
Publicado: (2020)

The Frequency of Clinical Seizures in Paroxysmal Events in a Neonatal Intensive Care Unit
por: Chan, Oi-Wa, et al.
Publicado: (2022)

Electrographic Seizures in Neonates with a High Risk of Encephalopathy
por: Chen, Wan-Hsuan, et al.
Publicado: (2022)

Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in Sepsis
por: Okamoto, Takayuki, et al.
Publicado: (2012)

Value of Serum Thrombomodulin as a Marker and Predictor in Patients with Sepsis-Associated Acute Kidney Injury
por: Nguyen, Van Tri, et al.
Publicado: (2023)

Thrombomodulin Promotes Corneal Epithelial Wound Healing
por: Huang, Yi-Hsun, et al.
Publicado: (2015)

Clinical application of target temperature management in children with acute encephalopathy–A practical review
por: Lin, Jainn-Jim, et al.
Publicado: (2020)

Epidemiology and clinical analysis of critical patients with child maltreatment admitted to the intensive care units
por: Lee, En-Pei, et al.
Publicado: (2017)

MRI of fatal course of acute hemorrhagic leukoencephalitis in a child with SARS-CoV-2 omicron BA 2.0 infection
por: Wong, Alex Mun-Ching, et al.
Publicado: (2023)

Benefit profile of recombinant human soluble thrombomodulin in sepsis-induced DIC
por: Yamakawa, K, et al.
Publicado: (2014)

Adequate application of recombinant thrombomodulin for sepsis-associated disseminated intravascular coagulation
por: Iba, Toshiaki
Publicado: (2015)

Markers of acute kidney injury in patients with sepsis: the role of soluble thrombomodulin
por: Katayama, Shinshu, et al.
Publicado: (2017)

Recombinant human soluble thrombomodulin improves mortality in patients with sepsis especially for severe coagulopathy: a retrospective study
por: Kato, Takahiro, et al.
Publicado: (2018)

COVID-19–associated acute necrotizing encephalopathy in a 3-year-old child
por: Liu, Hung-Hsien, et al.
Publicado: (2023)

The role of thrombomodulin lectin-like domain in inflammation
por: Li, Yi-Heng, et al.
Publicado: (2012)

Detecting hypercoagulability in sepsis: thromboelastometry vs thrombomodulin-modified thrombin generation test
por: Osovskikh, VV, et al.
Publicado: (2015)

Association between thrombomodulin and high mobility group box 1 in sepsis patients
por: Rodrigues, Adriana Teixeira, et al.
Publicado: (2020)

Thrombomodulin gene polymorphism and the occurrence and prognostic value of sepsis acute kidney injury
por: Li, Qin, et al.
Publicado: (2021)

Recombinant human soluble thrombomodulin administration improves sepsis-induced disseminated intravascular coagulation and mortality: a retrospective cohort study
por: Kato, Takahiro, et al.
Publicado: (2013)

Effect of a Recombinant Human Soluble Thrombomodulin on Baseline Coagulation Biomarker Levels and Mortality Outcome in Patients With Sepsis-Associated Coagulopathy
por: Levi, Marcel, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_31ikivp9dk4vhp0nispv0n772k