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Absence of microRNA-21 does not reduce muscular dystrophy in mouse models of LAMA2-CMD

MicroRNAs (miRNAs) are short non-coding RNAs that modulate gene expression post-transcriptionally. Current evidence suggests that miR-21 plays a significant role in the progression of fibrosis in muscle diseases. Laminin-deficient congenital muscular dystrophy (LAMA2-CMD) is a severe form of congeni...

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Detalles Bibliográficos
Autores principales:	Moreira Soares Oliveira, Bernardo, Durbeej, Madeleine, Holmberg, Johan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542641/ https://www.ncbi.nlm.nih.gov/pubmed/28771630 http://dx.doi.org/10.1371/journal.pone.0181950

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