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Ester alkaloids from Cephalotaxus interfere with the 2’3’-cGAMP-induced type I interferon pathway in vitro

Dysregulated activation of the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway by self-DNA contributes to interferonopathy and promotes autoimmune diseases. To identify potential suppressors of STING-induced type I interferon (IFN) induction, ethanol extracts of medicinal...

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Detalles Bibliográficos
Autores principales:	Park, Gayoung, Kim, Sun Yeou, Song, Yoon-Jae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542643/ https://www.ncbi.nlm.nih.gov/pubmed/28771599 http://dx.doi.org/10.1371/journal.pone.0182701

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