Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge

Statins, the 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors, are widely prescribed for treatment of hypercholesterolemia. Although statins are generally well tolerated, up to ten percent of statin-treated patients experience myalgia symptoms, defined as muscle pain without elevated creat...

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Detalles Bibliográficos
Autores principales: Elam, Marshall B., Majumdar, Gipsy, Mozhui, Khyobeni, Gerling, Ivan C., Vera, Santiago R., Fish-Trotter, Hannah, Williams, Robert W., Childress, Richard D., Raghow, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542661/
https://www.ncbi.nlm.nih.gov/pubmed/28771594
http://dx.doi.org/10.1371/journal.pone.0181308

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