Regulation of type 1 diabetes development and B-cell activation in nonobese diabetic mice by early life exposure to a diabetogenic environment

Microbes, including viruses, influence type 1 diabetes (T1D) development, but many such influences remain undefined. Previous work on underlying immune mechanisms has focussed on cytokines and T cells. Here, we compared two nonobese diabetic (NOD) mouse colonies, NOD(low) and NOD(high), differing ma...

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Detalles Bibliográficos
Autores principales: De Riva, Alessandra, Wållberg, Maja, Ronchi, Francesca, Coulson, Richard, Sage, Andrew, Thorne, Lucy, Goodfellow, Ian, McCoy, Kathy D., Azuma, Miyuki, Cooke, Anne, Busch, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542673/
https://www.ncbi.nlm.nih.gov/pubmed/28771521
http://dx.doi.org/10.1371/journal.pone.0181964

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