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Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei

All cells are subject to structural damage that must be addressed for continued growth. A wide range of damage affects the genome, meaning multiple pathways have evolved to repair or bypass the resulting DNA lesions. Though many repair pathways are conserved, their presence or function can reflect t...

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Detalles Bibliográficos
Autores principales:	Stortz, Jennifer A., Serafim, Tiago D., Alsford, Sam, Wilkes, Jonathan, Fernandez-Cortes, Fernando, Hamilton, Graham, Briggs, Emma, Lemgruber, Leandro, Horn, David, Mottram, Jeremy C., McCulloch, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542689/ https://www.ncbi.nlm.nih.gov/pubmed/28742144 http://dx.doi.org/10.1371/journal.ppat.1006477

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