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Pathological manifestations in lymphatic filariasis correlate with lack of inhibitory properties of IgG4 antibodies on IgE-activated granulocytes

Helminth parasites are known to be efficient modulators of their host’s immune system. To guarantee their own survival, they induce alongside the classical Th2 a strong regulatory response with high levels of anti-inflammatory cytokines and elevated plasma levels of IgG4. This particular antibody wa...

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Detalles Bibliográficos
Autores principales:	Prodjinotho, Ulrich F., von Horn, Charlotte, Debrah, Alex Y., Batsa Debrah, Linda, Albers, Anna, Layland, Laura E., Hoerauf, Achim, Adjobimey, Tomabu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542694/ https://www.ncbi.nlm.nih.gov/pubmed/28742098 http://dx.doi.org/10.1371/journal.pntd.0005777

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