Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes

Hsp70 participates in a broad spectrum of protein folding processes extending from nascent chain folding to protein disaggregation. This versatility in function is achieved through a diverse family of J-protein cochaperones that select substrates for Hsp70. Substrate selection is further tuned by tr...

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Detalles Bibliográficos
Autores principales: Nillegoda, Nadinath B, Stank, Antonia, Malinverni, Duccio, Alberts, Niels, Szlachcic, Anna, Barducci, Alessandro, De Los Rios, Paolo, Wade, Rebecca C, Bukau, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542770/
https://www.ncbi.nlm.nih.gov/pubmed/28504929
http://dx.doi.org/10.7554/eLife.24560

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