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Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance
Therapies targeting signaling molecules mutated in cancers can often have striking short-term effects, but the emergence of resistant cancer cells is a major barrier to full cures(1,2). Resistance can result from a secondary mutations(3,4), but other times there is no clear genetic cause, raising th...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542814/ https://www.ncbi.nlm.nih.gov/pubmed/28607484 http://dx.doi.org/10.1038/nature22794 |