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Epigenetic dysregulation of ID4 predicts disease progression and treatment outcome in myeloid malignancies

Promoter hypermethylation‐mediated inactivation of ID4 plays a crucial role in the development of solid tumours. This study aimed to investigate ID4 methylation and its clinical relevance in myeloid malignancies. ID4 hypermethylation was associated with higher IPSS scores, but was not an independent...

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Detalles Bibliográficos
Autores principales: Zhou, Jing‐dong, Zhang, Ting‐juan, Li, Xi‐xi, Ma, Ji‐chun, Guo, Hong, Wen, Xiang‐mei, Zhang, Wei, Yang, Lei, Yan, Yang, Lin, Jiang, Qian, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5542913/
https://www.ncbi.nlm.nih.gov/pubmed/28452111
http://dx.doi.org/10.1111/jcmm.13073