Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas

Cranial radiotherapy improves survival of the most common childhood cancers, including brain tumors and leukemia. Unfortunately, long-term survivors are faced with consequences of secondary neoplasia, including radiation-induced meningiomas (RIMs). We characterized 31 RIMs with exome/NF2 intronic se...

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Detalles Bibliográficos
Autores principales: Agnihotri, Sameer, Suppiah, Suganth, Tonge, Peter D., Jalali, Shahrzad, Danesh, Arnavaz, Bruce, Jeffery P., Mamatjan, Yasin, Klironomos, George, Gonen, Lior, Au, Karolyn, Mansouri, Sheila, Karimi, Sharin, Sahm, Felix, von Deimling, Andreas, Taylor, Michael D., Laperriere, Normand J., Pugh, Trevor J., Aldape, Kenneth D., Zadeh, Gelareh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543118/
https://www.ncbi.nlm.nih.gov/pubmed/28775249
http://dx.doi.org/10.1038/s41467-017-00174-7

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