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Structural basis of Notch O-glucosylation and O–xylosylation by mammalian protein–O-glucosyltransferase 1 (POGLUT1)

Protein O-glucosyltransferase 1/Rumi-mediated glucosylation of Notch epidermal growth factor-like (EGF-like) domains plays an important role in Notch signaling. Protein O-glucosyltransferase 1 shows specificity for folded EGF-like domains, it can only glycosylate serine residues in the C(1)XSXPC(2)...

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Detalles Bibliográficos
Autores principales:	Li, Zhijie, Fischer, Michael, Satkunarajah, Malathy, Zhou, Dongxia, Withers, Stephen G., Rini, James M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543122/ https://www.ncbi.nlm.nih.gov/pubmed/28775322 http://dx.doi.org/10.1038/s41467-017-00255-7

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