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Modulation of activation and inactivation by Ca(2+) and 2-APB in the pore of an archetypal TRPM channel from Nematostella vectensis

The archetypal TRPM2-like channel of the sea anemone Nematostella vectensis is gated by ADPR like its human orthologue but additionally exhibits properties of other vertebrate TRPM channels. Thus it can help towards an understanding of gating and regulation of the whole subfamily. To elucidate furth...

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Detalles Bibliográficos
Autores principales:	Kühn, Frank J. P., Mathis, Winking, Cornelia, Kühn, Hoffmann, Daniel C., Lückhoff, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543165/ https://www.ncbi.nlm.nih.gov/pubmed/28775320 http://dx.doi.org/10.1038/s41598-017-07652-4

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