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Hepatic cyclooxygenase-2 overexpression induced spontaneous hepatocellular carcinoma formation in mice

Cyclooxygenase (COX)-2 is upregulated in hepatocellular carcinoma (HCC). However, the direct causative effect of COX-2 in spontaneous HCC formation remains unknown. We thus investigate the role and molecular pathogenesis of COX-2 in HCC by using liver-specific COX-2 transgenic (TG) mice. We found sp...

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Detalles Bibliográficos
Autores principales:	Chen, H, Cai, W, Chu, E S H, Tang, J, Wong, C-C, Wong, S H, Sun, W, Liang, Q, Fang, J, Sun, Z, Yu, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543258/ https://www.ncbi.nlm.nih.gov/pubmed/28346420 http://dx.doi.org/10.1038/onc.2017.73

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