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Identification and characterization of a novel botulinum neurotoxin

Botulinum neurotoxins are known to have seven serotypes (BoNT/A–G). Here we report a new BoNT serotype, tentatively named BoNT/X, which has the lowest sequence identity with other BoNTs and is not recognized by antisera against known BoNTs. Similar to BoNT/B/D/F/G, BoNT/X cleaves vesicle-associated...

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Detalles Bibliográficos
Autores principales: Zhang, Sicai, Masuyer, Geoffrey, Zhang, Jie, Shen, Yi, Lundin, Daniel, Henriksson, Linda, Miyashita, Shin-Ichiro, Martínez-Carranza, Markel, Dong, Min, Stenmark, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543303/
https://www.ncbi.nlm.nih.gov/pubmed/28770820
http://dx.doi.org/10.1038/ncomms14130