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Conventional NK cells and ILC1 are partially ablated in the livers of Ncr1 (iCre)Tbx21 (fl/fl) mice
Mouse liver contains both Eomes-dependent conventional natural killer (cNK) cells and Tbet-dependent liver-resident type I innate lymphoid cells (ILC1). In order to better understand the role of ILC1, we attempted to generate mice that would lack liver ILC1, while retaining cNK, by conditional delet...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543419/ https://www.ncbi.nlm.nih.gov/pubmed/28815219 http://dx.doi.org/10.12688/wellcomeopenres.11741.2 |