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Identification of candidate protective variants for common diseases and evaluation of their protective potential

BACKGROUND: Human polymorphisms with derived alleles that are protective against disease may provide powerful translational opportunities. Here we report a method to identify such candidate polymorphisms and apply it to common non-synonymous SNPs (nsSNPs) associated with common diseases. Our study a...

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Detalles Bibliográficos
Autores principales:	Butler, Joe M., Hall, Neil, Narendran, Niro, Yang, Yit C., Paraoan, Luminita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543444/ https://www.ncbi.nlm.nih.gov/pubmed/28774272 http://dx.doi.org/10.1186/s12864-017-3964-3

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