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Plasmid-mediated mcr-1 colistin resistance in Escherichia coli and Klebsiella spp. clinical isolates from the Western Cape region of South Africa

BACKGROUND: Colistin is a last resort antibiotic for the treatment of carbapenem-resistant Gram negative infections. Until recently, mechanisms of colistin resistance were limited to chromosomal mutations which confer a high fitness cost and cannot be transferred between organisms. However, a novel...

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Detalles Bibliográficos
Autores principales:	Newton-Foot, Mae, Snyman, Yolandi, Maloba, Motlatji Reratilwe Bonnie, Whitelaw, Andrew Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543748/ https://www.ncbi.nlm.nih.gov/pubmed/28785405 http://dx.doi.org/10.1186/s13756-017-0234-8

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