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GASTRIC NEUROENDOCRINE TUMOR: REVIEW AND UPDATE

INTRODUCTION: The frequency of gastric neuroendocrine tumors is increasing. Reasons are the popularization of endoscopy and its technical refinements. Despite this, they are still poorly understood and have complex management. AIM: Update the knowledge on gastric neuroendocrine tumor and expose the...

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Detalles Bibliográficos
Autores principales: DIAS, Andre Roncon, AZEVEDO, Beatriz Camargo, ALBAN, Luciana Bastos Valente, YAGI, Osmar Kenji, RAMOS, Marcus Fernando Kodama Pertille, JACOB, Carlos Eduardo, BARCHI, Leandro Cardoso, CECCONELLO, Ivan, RIBEIRO-JR, Ulysses, ZILBERSTEIN, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543797/
https://www.ncbi.nlm.nih.gov/pubmed/29257854
http://dx.doi.org/10.1590/0102-6720201700020016
Descripción
Sumario:INTRODUCTION: The frequency of gastric neuroendocrine tumors is increasing. Reasons are the popularization of endoscopy and its technical refinements. Despite this, they are still poorly understood and have complex management. AIM: Update the knowledge on gastric neuroendocrine tumor and expose the future perspectives on the diagnosis and treatment of this disease. METHOD: Literature review using the following databases: Medline/PubMed, Cochrane Library and SciELO. Search terms were: gastric carcinoid, gastric neuroendocrine tumor, treatment. From the selected articles, 38 were included in this review. RESULTS: Gastric neuroendocrine tumors are classified in four clinical types. Correct identification of the clinical type and histological grade is fundamental, since treatment varies accordingly and defines survival. CONCLUSION: Gastric neuroendocrine tumors comprise different subtypes with distinct management and prognosis. Correct identification allows for a tailored therapy. Further studies will clarify the diseases biology and improve its treatment.