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1.12 Å resolution crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2
MCR-2 confers resistance to colistin, a ‘last-line’ antibiotic against extensively resistant Gram-negative pathogens. It is a plasmid-encoded phosphoethanolamine transferase that is closely related to MCR-1. To understand the diversity in the MCR family, the 1.12 Å resolution crystal structure of t...
Autores principales: | Coates, Katie, Walsh, Timothy R., Spencer, James, Hinchliffe, Philip |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544000/ https://www.ncbi.nlm.nih.gov/pubmed/28777086 http://dx.doi.org/10.1107/S2053230X17009669 |
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