Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells

Epithelia act as a barrier between the internal and external environments, and the movement of substances via the paracellular pathway is regulated by tight junctions (TJs). Claudins are major determinants of TJ permeability. Claudin-4 was the first claudin whose involvement in the TJ permeability i...

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Detalles Bibliográficos
Autores principales: Tokuda, Shinsaku, Hirai, Toyohiro, Furuse, Mikio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544209/
https://www.ncbi.nlm.nih.gov/pubmed/28777806
http://dx.doi.org/10.1371/journal.pone.0182521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544209/
https://www.ncbi.nlm.nih.gov/pubmed/28777806
http://dx.doi.org/10.1371/journal.pone.0182521

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