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Mechanical instability and titanium particles induce similar transcriptomic changes in a rat model for periprosthetic osteolysis and aseptic loosening

Wear debris particles released from prosthetic bearing surfaces and mechanical instability of implants are two main causes of periprosthetic osteolysis. While particle-induced loosening has been studied extensively, mechanisms through which mechanical factors lead to implant loosening have been less...

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Detalles Bibliográficos
Autores principales: Amirhosseini, Mehdi, Andersson, Göran, Aspenberg, Per, Fahlgren, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544474/
https://www.ncbi.nlm.nih.gov/pubmed/28795083
http://dx.doi.org/10.1016/j.bonr.2017.07.003