CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation

The NLRP3 inflammasome can sense different pathogens or danger signals, and has been reported to be involved in the development of many human diseases. Potassium efflux and mitochondrial damage are both reported to mediate NLRP3 inflammasome activation, but the underlying, orchestrating signaling ev...

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Detalles Bibliográficos
Autores principales: Tang, Tiantian, Lang, Xueting, Xu, Congfei, Wang, Xiaqiong, Gong, Tao, Yang, Yanqing, Cui, Jun, Bai, Li, Wang, Jun, Jiang, Wei, Zhou, Rongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544706/
https://www.ncbi.nlm.nih.gov/pubmed/28779175
http://dx.doi.org/10.1038/s41467-017-00227-x

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