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Generation of Myostatin Gene-Edited Channel Catfish (Ictalurus punctatus) via Zygote Injection of CRISPR/Cas9 System
The myostatin (MSTN) gene is important because of its role in regulation of skeletal muscle growth in all vertebrates. In this study, CRISPR/Cas9 was utilized to successfully target the channel catfish, Ictalurus punctatus, muscle suppressor gene MSTN. CRISPR/Cas9 induced high rates (88–100%) of mut...
Autores principales: | Khalil, Karim, Elayat, Medhat, Khalifa, Elsayed, Daghash, Samer, Elaswad, Ahmed, Miller, Michael, Abdelrahman, Hisham, Ye, Zhi, Odin, Ramjie, Drescher, David, Vo, Khoi, Gosh, Kamal, Bugg, William, Robinson, Dalton, Dunham, Rex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544710/ https://www.ncbi.nlm.nih.gov/pubmed/28779173 http://dx.doi.org/10.1038/s41598-017-07223-7 |
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