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Vitamin D attenuates myofibroblast differentiation and extracellular matrix accumulation in nasal polyp-derived fibroblasts through smad2/3 signaling pathway

To investigate the potential role of vitamin D (1,25(OH)(2)D(3)) in preventing the development of nasal polyps, we examined the effect of vitamin D on myofibroblast differentiation and extracellular matrix (ECM) production in TGF-β1-induced nasal polyp-derived fibroblasts (NPDFs) and elucidated the...

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Detalles Bibliográficos
Autores principales:	Lee, Seoung-Ae, Yang, Hyun-Woo, Um, Ji-Young, Shin, Jae-Min, Park, Il-Ho, Lee, Heung-Man
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544725/ https://www.ncbi.nlm.nih.gov/pubmed/28779150 http://dx.doi.org/10.1038/s41598-017-07561-6

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