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Association between duration of coronary occlusion and high-intensity signal on T1-weighted magnetic resonance imaging among patients with angiographic total occlusion

OBJECTIVES: To evaluate the association between duration of the coronary occlusion and high-intensity signal (HIS) on noncontrast T1-weighted imaging using a 1.5-T magnetic resonance imager among patients with angiographic coronary total occlusion. METHODS: The signal intensity of the coronary targe...

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Detalles Bibliográficos
Autores principales: Matsumoto, Kenji, Ehara, Shoichi, Hasegawa, Takao, Sakaguchi, Mikumo, Shimada, Kenei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544795/
https://www.ncbi.nlm.nih.gov/pubmed/28155111
http://dx.doi.org/10.1007/s00330-016-4672-0
Descripción
Sumario:OBJECTIVES: To evaluate the association between duration of the coronary occlusion and high-intensity signal (HIS) on noncontrast T1-weighted imaging using a 1.5-T magnetic resonance imager among patients with angiographic coronary total occlusion. METHODS: The signal intensity of the coronary target area divided by the signal intensity of the left ventricular muscle near the target area at each site (TMR) was measured. Areas with a TMR >1.0 were defined as HIS. Thirty five lesions from 33 patients were divided into the following three groups: subacute occlusion (up to 3 months; n = 7), short-duration chronic total occlusion (SD-CTO: 3–6 months; n = 9) and long-duration CTO (LD-CTO: ≥6 months; n = 19). RESULTS: All subacute occlusion lesions showed a HIS within the occlusion site. Among patients with CTO, the frequency of a HIS within the occlusion site was significantly higher in SD-CTO than in LD-CTO lesions (p = 0.013). In multivariate analyses, only an occlusion duration of less than 6 months was an independent factor associated with the presence of HIS (odds ratio 7.6, 95% CI 1.1–54.5; p = 0.044). CONCLUSIONS: The presence of a HIS in the occlusion site was associated more with SD-CTO than with LD-CTO among patients with CTO. KEY POINTS: • All subacute occlusion lesions show a high-intensity signal on T1-weighted imaging. • HIS within occlusion sites is associated with subacute or short-duration total occlusion. • T1-weighted imaging for coronary total occlusion may be useful for intervention strategy.