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Immobilisation of Delta-like 1 ligand for the scalable and controlled manufacture of hematopoietic progenitor cells in a stirred bioreactor

BACKGROUND: Umbilical cord blood provides a source of hematopoietic stem cells for transplantation with immunological and availability advantages over conventional bone marrow sources. Limited cell numbers and slower engraftment from umbilical cord blood units has led to the clinical development of...

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Detalles Bibliográficos
Autores principales: Moore, Rebecca L. L., Worrallo, Matthew J., Mitchell, Peter D., Harriman, Jon, Glen, Katie E., Thomas, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544980/
https://www.ncbi.nlm.nih.gov/pubmed/28778182
http://dx.doi.org/10.1186/s12896-017-0383-0