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Is age a risk factor for liver disease and metabolic alterations in ataxia Telangiectasia patients?
BACKGROUND: Ataxia telangiectasia (A-T) is a neurodegenerative disease that leads to mitochondrial dysfunction and oxidative stress. Insulin resistance (IR), type 2 diabetes and the risk for development of cardiovascular disease was recently associated as an extended phenotype of the disease. We aim...
Autores principales: | Paulino, Talita Lemos, Rafael, Marina Neto, Hix, Sonia, Shigueoka, David Carlos, Ajzen, Sergio Aron, Kochi, Cristiane, Suano-Souza, Fabíola Isabel, da Silva, Rosangela, Costa-Carvalho, Beatriz T., Sarni, Roseli O. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545012/ https://www.ncbi.nlm.nih.gov/pubmed/28778179 http://dx.doi.org/10.1186/s13023-017-0689-y |
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