Limited survivability of unbalanced progeny of carriers of a unique t(4;19)(p15.32;p13.3): a study in multiple generations

BACKGROUND: Carriership of a reciprocal chromosomal translocation (RCT) involving the short arm of chromosome 4 (4p) may result in birth of a child with Wolf-Hirschhorn syndrome (WHS) due to monosomy 4p, a priori modified by the impact of the partner chromosome imbalance. Familial transmission studi...

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Detalles Bibliográficos
Autores principales: Šumanović-Glamuzina, Darinka, Lozić, Bernarda, Iwanowski, Piotr S., Zemunik, Tatijana, Bilinovac, Zeljka, Stasiewicz-Jarocka, Beata, Panasiuk, Barbara, Midro, Alina T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545035/
https://www.ncbi.nlm.nih.gov/pubmed/28785312
http://dx.doi.org/10.1186/s13039-017-0330-8

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