Ex-vivo models of the Retinal Pigment Epithelium (RPE) in long-term culture faithfully recapitulate key structural and physiological features of native RPE

The Retinal Pigment Epithelium (RPE) forms the primary site of pathology in several blinding retinopathies. RPE cultures are being continuously refined so that dynamic disease processes in this important monolayer can be faithfully studied outside the eye over longer periods. The RPE substrate, whic...

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Detalles Bibliográficos
Autores principales: Lynn, Savannah A., Ward, Gareth, Keeling, Eloise, Scott, Jenny A., Cree, Angela J., Johnston, David A., Page, Anton, Cuan-Urquizo, Enrique, Bhaskar, Atul, Grossel, Martin C., Tumbarello, David A., Newman, Tracey A., Lotery, Andrew J., Ratnayaka, J. Arjuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Churchill Livingstone 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545183/
https://www.ncbi.nlm.nih.gov/pubmed/28669519
http://dx.doi.org/10.1016/j.tice.2017.06.003

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