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Dosimetry for lung tumorigenesis induced by urethane, 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and benzo[a]pyrene (B[a]P) in A/JJmsSlc mice

Some chemicals are known to be lung carcinogens in rodents. While many studies using two-stage models have administered medium or high doses to mice, few have tested lower doses. The dose dependence of urethane, 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK), and benzo[a]pyrene (B[a]P), t...

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Detalles Bibliográficos
Autores principales:	Onami, Saeko, Okubo, Chigusa, Iwanaga, Asuka, Suzuki, Hiroaki, Iida, Hajime, Motohashi, Yurie, Tomonari, Yuki, Otake, Seiji, Tsuji, Hiroyuki, Yoshimura, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Japanese Society of Toxicologic Pathology 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545673/ https://www.ncbi.nlm.nih.gov/pubmed/28798528 http://dx.doi.org/10.1293/tox.2017-0005

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