DRD2 co-expression network and a related polygenic index predict imaging, behavioral and clinical phenotypes linked to schizophrenia

Genetic risk for schizophrenia (SCZ) is determined by many genetic loci whose compound biological effects are difficult to determine. We hypothesized that co-expression pathways of SCZ risk genes are associated with system-level brain function and clinical phenotypes of SCZ. We examined genetic vari...

Descripción completa

Detalles Bibliográficos
Autores principales: Pergola, G, Di Carlo, P, D'Ambrosio, E, Gelao, B, Fazio, L, Papalino, M, Monda, A, Scozia, G, Pietrangelo, B, Attrotto, M, Apud, J A, Chen, Q, Mattay, V S, Rampino, A, Caforio, G, Weinberger, D R, Blasi, G, Bertolino, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545721/
https://www.ncbi.nlm.nih.gov/pubmed/28094815
http://dx.doi.org/10.1038/tp.2016.253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545721/
https://www.ncbi.nlm.nih.gov/pubmed/28094815
http://dx.doi.org/10.1038/tp.2016.253

Ejemplares similares