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Antidepressant responsiveness in adulthood is permanently impaired after neonatal destruction of the neurogenic pool

The dynamic turnover of hippocampal neurons is implicated in the regulation of cognitive and affective behavior. Extending our previous demonstration that administration of dexamethasone (ND) to neonatal rats depletes the resident population of neural precursor cells (NPC) and restrains the size of...

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Detalles Bibliográficos
Autores principales: Yu, S, Zutshi, I, Stoffel, R, Zhang, J, Ventura-Silva, A P, Sousa, N, Costa, P S, Holsboer, F, Patchev, A, Almeida, O F X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545723/
https://www.ncbi.nlm.nih.gov/pubmed/28045461
http://dx.doi.org/10.1038/tp.2016.255