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Antidepressant responsiveness in adulthood is permanently impaired after neonatal destruction of the neurogenic pool
The dynamic turnover of hippocampal neurons is implicated in the regulation of cognitive and affective behavior. Extending our previous demonstration that administration of dexamethasone (ND) to neonatal rats depletes the resident population of neural precursor cells (NPC) and restrains the size of...
Autores principales: | Yu, S, Zutshi, I, Stoffel, R, Zhang, J, Ventura-Silva, A P, Sousa, N, Costa, P S, Holsboer, F, Patchev, A, Almeida, O F X |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545723/ https://www.ncbi.nlm.nih.gov/pubmed/28045461 http://dx.doi.org/10.1038/tp.2016.255 |
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