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Alcohol-dose-dependent DNA methylation and expression in the nucleus accumbens identifies coordinated regulation of synaptic genes

Alterations in DNA methylation have been associated with alcohol exposure and proposed to contribute to continued alcohol use; however, the molecular mechanisms involved remain obscure. We investigated the escalating effects of alcohol use on DNA methylation, gene expression and predicted neural eff...

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Detalles Bibliográficos
Autores principales: Cervera-Juanes, R, Wilhelm, L J, Park, B, Grant, K A, Ferguson, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545731/
https://www.ncbi.nlm.nih.gov/pubmed/28072409
http://dx.doi.org/10.1038/tp.2016.266