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Early onset of inflammation during ontogeny of bipolar disorder: the NLRP2 inflammasome gene distinctly differentiates between patients and healthy controls in the transition between iPS cell and neural stem cell stages

Neuro-inflammation and neuronal communication are considered as mis-regulated processes in the aetiology and pathology of bipolar disorder (BD). Which and when specific signal pathways become abnormal during the ontogeny of bipolar disorder patients is unknown. To address this question, we applied i...

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Detalles Bibliográficos
Autores principales: Vizlin-Hodzic, D, Zhai, Q, Illes, S, Södersten, K, Truvé, K, Parris, T Z, Sobhan, P K, Salmela, S, Kosalai, S T, Kanduri, C, Strandberg, J, Seth, H, Bontell, T O, Hanse, E, Ågren, H, Funa, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545741/
https://www.ncbi.nlm.nih.gov/pubmed/28117838
http://dx.doi.org/10.1038/tp.2016.284