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The Montreal Cognitive Assessment: Normative Data from a Large Swedish Population-Based Cohort
BACKGROUND: The Montreal Cognitive Assessment (MoCA) has a high sensitivity for detecting cognitive dysfunction. Swedish normative data does not exist and international norms are often derived from populations where cognitive impairment has not been screened for and not been thoroughly assessed to e...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545909/ https://www.ncbi.nlm.nih.gov/pubmed/28697562 http://dx.doi.org/10.3233/JAD-170203 |
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author | Borland, Emma Nägga, Katarina Nilsson, Peter M. Minthon, Lennart Nilsson, Erik D. Palmqvist, Sebastian |
author_facet | Borland, Emma Nägga, Katarina Nilsson, Peter M. Minthon, Lennart Nilsson, Erik D. Palmqvist, Sebastian |
author_sort | Borland, Emma |
collection | PubMed |
description | BACKGROUND: The Montreal Cognitive Assessment (MoCA) has a high sensitivity for detecting cognitive dysfunction. Swedish normative data does not exist and international norms are often derived from populations where cognitive impairment has not been screened for and not been thoroughly assessed to exclude subjects with dementia or mild cognitive impairment. OBJECTIVE: To establish norms for MoCA and develop a regression-based norm calculator based on a large, well-examined cohort. METHODS: MoCA was administered on 860 randomly selected elderly people from a population-based cohort from the EPIC study. Cognitive dysfunction was screened for and further assessed at a memory clinic. After excluding cognitively impaired participants, normative data was derived from 758 people, aged 65–85. RESULTS: MoCA cut-offs (–1 to –2 standard deviations) for cognitive impairment ranged from <25 to <21 for the lowest educated and <26 to <24 for the highest educated, depending on age group. Significant predictors for MoCA score were age, sex and level of education. CONCLUSION: We present detailed normative MoCA data and cut-offs according to the DSM-5 criteria for cognitive impairment based on a large population-based cohort of elderly individuals, screened and thoroughly investigated to rule out cognitive impairment. Level of education, sex, and age should be taken in account when evaluating MoCA score, which is facilitated by our online regression-based calculator that provide percentile and z-score for a subject’s MoCA score. |
format | Online Article Text |
id | pubmed-5545909 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | IOS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-55459092017-08-16 The Montreal Cognitive Assessment: Normative Data from a Large Swedish Population-Based Cohort Borland, Emma Nägga, Katarina Nilsson, Peter M. Minthon, Lennart Nilsson, Erik D. Palmqvist, Sebastian J Alzheimers Dis Research Article BACKGROUND: The Montreal Cognitive Assessment (MoCA) has a high sensitivity for detecting cognitive dysfunction. Swedish normative data does not exist and international norms are often derived from populations where cognitive impairment has not been screened for and not been thoroughly assessed to exclude subjects with dementia or mild cognitive impairment. OBJECTIVE: To establish norms for MoCA and develop a regression-based norm calculator based on a large, well-examined cohort. METHODS: MoCA was administered on 860 randomly selected elderly people from a population-based cohort from the EPIC study. Cognitive dysfunction was screened for and further assessed at a memory clinic. After excluding cognitively impaired participants, normative data was derived from 758 people, aged 65–85. RESULTS: MoCA cut-offs (–1 to –2 standard deviations) for cognitive impairment ranged from <25 to <21 for the lowest educated and <26 to <24 for the highest educated, depending on age group. Significant predictors for MoCA score were age, sex and level of education. CONCLUSION: We present detailed normative MoCA data and cut-offs according to the DSM-5 criteria for cognitive impairment based on a large population-based cohort of elderly individuals, screened and thoroughly investigated to rule out cognitive impairment. Level of education, sex, and age should be taken in account when evaluating MoCA score, which is facilitated by our online regression-based calculator that provide percentile and z-score for a subject’s MoCA score. IOS Press 2017-07-29 /pmc/articles/PMC5545909/ /pubmed/28697562 http://dx.doi.org/10.3233/JAD-170203 Text en © 2017 – IOS Press and the authors. All rights reserved https://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) License (https://creativecommons.org/licenses/by-nc/4.0/) , which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Borland, Emma Nägga, Katarina Nilsson, Peter M. Minthon, Lennart Nilsson, Erik D. Palmqvist, Sebastian The Montreal Cognitive Assessment: Normative Data from a Large Swedish Population-Based Cohort |
title | The Montreal Cognitive Assessment: Normative Data from a Large Swedish Population-Based Cohort |
title_full | The Montreal Cognitive Assessment: Normative Data from a Large Swedish Population-Based Cohort |
title_fullStr | The Montreal Cognitive Assessment: Normative Data from a Large Swedish Population-Based Cohort |
title_full_unstemmed | The Montreal Cognitive Assessment: Normative Data from a Large Swedish Population-Based Cohort |
title_short | The Montreal Cognitive Assessment: Normative Data from a Large Swedish Population-Based Cohort |
title_sort | montreal cognitive assessment: normative data from a large swedish population-based cohort |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5545909/ https://www.ncbi.nlm.nih.gov/pubmed/28697562 http://dx.doi.org/10.3233/JAD-170203 |
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